Rotary motion of DNA rotors on nanopores. Top row: Uncooked video with the Cy5 channel of each rotor. Center row: corresponding solitary-particle localization results of both equally ends of your DNA rotors. The placement of the present frame is marked as orange and blue dots, as well as trajectory of the 10 frames before The present body is proven as solid traces.
1996, to start with mesoscopic charge density waves units; and to start with electrical measurements on a single steel nanocluster involving nanoelectrodes
As being a human being, I provide the biblical assignment to take a look at and use every thing in development for the good thing about my neighbour. I never encounter any conflict in between faith and science. On the contrary, my religion stimulates me to carry out science, to be open-minded on earth.’
Nanofabrication of electrodes with sub-five nm spacing for transport experiments on solitary molecules and metallic clusters
2015, discovery that condensin is usually a remarkably versatile protein structure; and initially detection of DNA knots making use of nanopores
In the years next these discoveries, my investigate pursuits shifted to biophysics and nanobiology, and I became less linked to the event of nanotube electronics. The focus of numerous scientists in the sector also shifted to graphene (the place, funnily adequate, the very first graphene ribbons were being called ‘nanotubes which might be Lower open up alongside their length’) just after the invention of the two-dimensional product in 2004.
Size control of individual carbon nanotubes by nanostructuring with the scanning tunneling microscope
Dynamic ParB–DNA interactions initiate and maintain a partition condensate for bacterial chromosome segregation
What if, in place of making use of conventional top rated-down silicon electronics, transistors could possibly be crafted from the bottom up using solitary natural and organic molecules since the switching elements? This idea, which turned the basis of now’s industry of molecular electronics, very first emerged during the seventies.
Resolving the stage dimension in condensin-driven DNA loop extrusion identifies ATP binding as the step-generating process
An built-in microfluidic System for quantifying drug permeation across biomimetic vesicle membranes
1999, initial measurement with the wavefunction of single molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for just a new Luttinger description of interacting electrons in nanotubes
2005, discovery with the mechanism of DNA uncoiling by topoisomerase enzymes; discovery of prolonged-range conformational alterations in https://www.ceesdekker.net Mre11/DNA repair complexes; and 1st drive measurements on the DNA molecule in a very nanopore
‘I am driven by ponder and issues. On a cloth level I discover solutions in physics, but I knowledge my deepest pleasure with God. That religion also drives my science And exactly how I deal with individuals.